Dna plasmids having improved expression and stability

Details Dna plasmids having improved expression and stability Dna plasmids having improved expression and stability

C - Chemistry, Metallurgy

12

N

C12N 15/63 (2006.01)

Patent

CA 2684923

The present invention relates to compositions and methods to improve expression of exogenous polypeptides, such as an antigen, epitope, immunogen, peptide or polypeptide of interest. More particularly, the present invention provides for DNA plasmids with increased expression and stability in compositions and methods useful for DNA vaccines.

La présente invention concerne des compositions et des procédés permettant d'améliorer l'expression de polypeptides exogènes, tels qu'un antigène, un épitope, un immunogène, un peptide ou polypeptide d'intérêt. Plus particulièrement, la présente invention propose des plasmides à ADN dont l'expression et la stabilité sont améliorées dans des compositions et des procédés utiles pour les vaccins à ADN.

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