Dna polymerases having modified nucleotide binding site for...

Details Dna polymerases having modified nucleotide binding site for... Dna polymerases having modified nucleotide binding site for...

C - Chemistry, Metallurgy

12

N

C12N 15/54 (2006.01) C12M 1/34 (2006.01) C12M 1/40 (2006.01) C12N 9/12 (2006.01) C12N 15/01 (2006.01) C12N 15/10 (2006.01) C12P 19/34 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2201885

Modified gene encoding a modified DNA polymerase wherein the modified polymerase incorporates dideoxynucleotides at least 20--fold better compared to the corresponding deoxynucleotides as compared with the corresponding naturally-occurring DNA polymerase.

Gène modifié codant une ADN polymérase modifiée qui, par rapport à l'ADN polymérase naturelle correspondante, comprend des didésoxynucléotides au moins 20 fois plus efficaces que les désoxynucléotides correspondants.

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