Dna sequence and encoded mammary-specific breast cancer protein

Details Dna sequence and encoded mammary-specific breast cancer protein Dna sequence and encoded mammary-specific breast cancer protein

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) C07H 21/00 (2006.01) C07K 14/47 (2006.01) C12Q 1/68 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2222747

A purified and isolated DNA sequence and the encoded mammary-specific protein, mammaglobin, are disclosed. Also disclosed are methods for the detecting breast cancer based upon the overexpression and secretion of mammaglobin by breast cancer cells. The methods detect and/or quantitate the presence of mammaglobin or the mRNA encoding mammaglobin.

L'invention concerne une séquence purifiée et isolée d'ADN et la protéine codée spécifique de la glande mammaire, la mammaglobine. L'invention concerne également des procédés de dépistage du cancer du sein sur la base de la surexpression et de la sécrétion de mammaglobine par les cellules du cancer du sein. Ces procédés détectent et/ou quantifient la présence de mammaglobine ou de l'ARNm codant pour la mammaglobine.

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