C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/54 (2006.01) C07K 14/71 (2006.01) C07K 16/28 (2006.01) C12N 9/12 (2006.01) G01N 33/566 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2173102
The present invention relates to an isolated BMP receptor kinase protein or soluble fragment thereof, a DNA sequence coding for said BMP receptor kinase protein or said soluble fragment thereof, a recombinant expression vector comprising said DNA sequence, a host cell comprising said recombinant expression vector, a method of expressing said BMP receptor kinase protein or soluble fragment thereof, a method for identifying compounds capable of binding to said BMP receptor kinase protein or soluble fragment thereof, a method for the amount of such compounds in a sample, and antibodies to said BMP receptor kinase protein.
La présente invention concerne l'isolation d'une protéine-kinase réceptrice de la protéine morphogénétique osseuse ou d'un fragment soluble de celle-ci, une séquence d'ADN codant pour ladite protéine-kinase ou ledit fragment soluble de celle-ci, un vecteur d'expression recombiné comportant ladite séquence d'ADN, une cellule hôte comprenant ledit vecteur d'expression recombiné, un procédé d'expression de ladite protéine-kinase ou d'un fragment soluble de celle-ci, un procédé pour identifier un composé susceptible de se fixer à ladite protéine-kinase ou à un fragment soluble de celle-ci, un procédé pour déterminer la quantité de ces composés dans un échantillon, et des anticorps de ladite protéine-kinase.
Cook Jonathan Shaun
Correa Paul Elliott
Koenig Beth Broe
Rosenbaum Jan Susan
Ting Jerry
Kirby Eades Gale Baker
The Procter & Gamble Company
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