Dna sequence encoding bovine .alpha.-lactalbumin and methods...

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/85 (2006.01) A01K 67/027 (2006.01) A23C 9/00 (2006.01) C07K 14/76 (2006.01) C12N 5/10 (2006.01) C12N 15/12 (2006.01) C12Q 1/68 (2006.01)

Patent

CA 2093659

ThE present invention relates to the use of a mammary specific .alpha.- lactalbumin protein to assist in the production of recombinant proteins in mammals' milk. The invention also relates to the genetically engineered mammal that produces the desired recombinant product in its milk and to the products produced by the genetically engineered mammal, including the altered composition of milk and the semen which includes the desired .alpha.- lactalbumin protein DNA sequence.

Cette invention concerne l'utilisation d'une protéine de lactalbumine-alpha à spécificité mammaire pour produire des protéines de recombinaison dans le lait des mammifères. Cette invention concerne également le mammifère modifié par génie génétique qui produit le produit de recombinaison désiré dans son lait, ainsi que les produits fabriqués par le mammifère modifié par génie génétique, y compris la composition modifiée du lait et la semence qui renferme la séquence d'ADN de la protéine de lactalbumine-alpha désirée.

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