C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/29 (2006.01) A61K 47/48 (2006.01) C07H 21/04 (2006.01) C07K 14/415 (2006.01) C07K 16/16 (2006.01) C12N 15/63 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2115049
The present invention provides the nucleotide sequence for a synthetic gene for the plant toxin gelonin and a process for producing, cloning and expressing this synthetic gene. The DNA sequence for a synthetic gene for gelonin as shown in sequence ID No. 1. The present invention also provides expression vectors containing the DNA sequences for gelonin and cells trans- formed with these vectors. In addition, an immunotoxin comprising an antibody conjugated to the protein gelonin.
Beattie Kenneth L.
Rosenblum Michael G.
Borden Ladner Gervais Llp
Research Development Foundation
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