Dna-vaccines based on constructs derived from the genomes of...

A - Human Necessities – 61 – K

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A61K 48/00 (2006.01) A61K 39/00 (2006.01) A61K 39/245 (2006.01) A61P 31/00 (2006.01)

Patent

CA 2389693

Methods of eliciting an immune response in a subject by adminsitering one or more large genomic DNA fragments are provided. Also provided are methods of identifying sequences encoding antigenic polypeptides. Also provided are vaccine compositions comprising one or more large genomic DNA fragments.

La présente invention concerne des procédés permettant de déclencher une réponse immunitaire chez un sujet par administration d'un ou de plusieurs grands fragments d'ADN génomique. Cette invention concerne également des procédés servant à identifier des séquences codant pour des polypeptides antigéniques, ainsi que des compositions de vaccin comprenant un ou plusieurs grands fragments d'ADN génomique.

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