Dna virus microrna and methods for inhibiting same

Details Dna virus microrna and methods for inhibiting same Dna virus microrna and methods for inhibiting same

A - Human Necessities

61

K

A61K 48/00 (2006.01) C07H 21/04 (2006.01) C12N 15/86 (2006.01)

Patent

CA 2590604

The invention relates to an isolated nucleic acid molecule comprising the sequence of a DNA virus microRNA. In another embodiment, the invention relates to isolated single stranded DNA virus microRNA molecules and anti-DNA virus microRNA molecules. In a further embodiment, the invention relates to an isolated microRNP. The invention further provides methods for inhibiting microRNA activity in a cell.

L'invention concerne une molécule d'acide nucléique isolée comprenant la séquence d'un micro-ARN de virus à ADN. Dans un autre mode de réalisation, l'invention concerne des molécules isolées de micro-ARN de virus à ADN simple brin et des molécules de micro-ARN de virus à anti-ADN. Dans un autre mode de réalisation encore, l'invention concerne des procédés permettant d'inhiber l'activité de micro-ARN dans une cellule.

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