C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/34 (2006.01) A01H 5/00 (2006.01) A01N 57/16 (2006.01) C07H 21/00 (2006.01) C12N 5/10 (2006.01) C12N 15/82 (2006.01)
Patent
CA 2167701
The invention relates to a ribozyme comprising a hybridising region and a catalytic region wherein the hybridising region is capable of hybridising to at least part of a target mRNA sequence transcribed from a DNA molecule associated with a DNA virus capable of infecting plant cells, wherein said catalytic region is capable of cleaving said target mRNA sequence thereby substantially reducing replication, infection and/or assembly of said DNA virus.
L'invention porte sur des ribozymes comportant une zone d'hybridation et une zone de catalyse et dont la zone d'hybridation peut s'hybrider à au moins une partie d'une séquence cible d'ARNm transcrite à partir d'une molécule d'ADN associée à un virus à ADN susceptible d'infecter des cellules végétales. Ladite zone de catalyse est capable de cliver lesdites séquences cibles d'ARNm, ce qui réduit sensiblement la réplication et/ou l'assemblage dudit virus à ADN et ses capacités d'infection.
Baudino Sylvie
Comeau David
Dry Ian Barry
Gruber Veronique
Lenee Philippe
Gene Shears Pty Limited
Gowling Lafleur Henderson Llp
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