Docetaxel immunoassay

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 16/44 (2006.01) C07D 305/14 (2006.01) C07K 16/00 (2006.01) G01N 33/53 (2006.01) G01N 33/532 (2006.01) G01N 33/551 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2602790

Novel conjugates of docetaxel and novel docetaxel immunogens derived from the 7 and 10 positions of docetaxel and monoclonal antibodies generated by these docetaxel linked immunogens are useful in immunoassays for the quantification and monitoring of docetaxel in biological fluids.

L'invention concerne de nouveaux conjugués de docétaxel et de nouveaux immunogènes à docétaxel dérivés des positions 7 et 10 du docétaxel ainsi que des anticorps monoclonaux générés par ces immunogènes liés au docétaxel, lesquels sont utiles dans des immunodosages de quantification et de contrôle du docétaxel dans les liquides biologiques.

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