Domain-exchanged binding molecules, methods of use and...

Details Domain-exchanged binding molecules, methods of use and... Domain-exchanged binding molecules, methods of use and...

C - Chemistry, Metallurgy

07

K

C07K 16/44 (2006.01) A61K 39/395 (2006.01) A61P 31/00 (2006.01) A61P 31/18 (2006.01) A61P 35/00 (2006.01) C07K 16/10 (2006.01) C07K 16/28 (2006.01) C40B 40/10 (2006.01) G01N 33/53 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2525370

Methods for random or rational design of high affinity domain exchanged binding molecules and methods of use are provided herein. Also provided are libraries containing a plurality of such domain exchanged binding molecules.

L'invention concerne des procédés de conception aléatoire et rationnelle de molécules de liaison à échange de domaine et à affinité élevée, ainsi que des procédés d'utilisation. Elle se rapporte aussi à des banques de gènes contenant une pluralité de ces molécules de liaison à échange de domaine

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