Dominant negative members of the steroid/thyroid superfamily...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/62 (2006.01) A01K 67/027 (2006.01) C07K 14/72 (2006.01) C07K 19/00 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2057049

2057049 9014356 PCTABS00002 Disclosed are novel trans-repressing analog receptors wherein the ligand-binding domain(s) are modified versus wild type receptor, such novel receptors having repressed trans-activation transcription activation properties. Also disclosed are recombinant methods and means for preparing such receptors and assays using such receptors.

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