Dominant negative proteins and methods thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/19 (2006.01) A61K 38/19 (2006.01) C07K 14/52 (2006.01) C07K 14/525 (2006.01) C07K 19/00 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2472049

The invention relates to novel proteins with TNFSF antagonist activity and nucleic acids encoding these proteins. The invention further relates to the use of the novel proteins in the treatment of TNFSF-related disorders.

L'invention concerne de nouvelles protéines à activité antagoniste de la superfamille du facteur de nécrose tumorale (TNFSF) et des acides nucléiques codant ces protéines. L'invention concerne également l'utilisation de ces nouvelles protéines dans le traitement de troubles liés à la TNFSF.

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