C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/211, 260/246
C07D 471/04 (2006.01) A61K 31/47 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01)
Patent
CA 2021314
X-7071 -1- DOPAMINE AGONISTS The present invention relates to certain novel dopamine agonists which are useful in treating a variety of disorders including Parkinsonism, depression, hyper- tension, anxiety, glaucoma, sexual dysfunction and prolactin mediated disorders such as galactorrhea, amenorrhea, prolactinoma and the inhibition of post- partum lactation. D-2 dopamine agonists are known to have the ability to inhibit the secretion of prolactin. Accord- ingly, such compounds are useful in treating a variety of prolactin mediated disorders such as galactorrhea, amenorrhea, prolactinoma and the inhibition of post- partum lactation. Furthermore, such agonists have been found to favorably affect a wide variety of mammalian disorders including Parkinson's Syndrome, depression, hypertension, anxiety, glaucoma and sexual dysfunction. Given the wide variety of therapeutic uses for D-2 dopamine agonists any compound which can be shown to have such activity provides an important weapon in the treatment of a variety of disorders which commonly afflict the mammalian species.
Eli Lilly And Company
Gowling Lafleur Henderson Llp
LandOfFree
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