C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4985 (2006.01) A61P 25/00 (2006.01)
Patent
CA 2450315
The present invention relates to compounds designed as ligands (e.g., agonists, antagonists, and partial agonists) for dopamine receptors (e.g., D1, D2, D3, D4, and D5), and in particular, the D1, D2, and D3 dopamine receptors. The present invention also relates to methods for rationally designing these compounds and to therapeutic methods of using these compounds.
La présente invention concerne des composés désignés comme ligands (<i>e</i>.<i>g</i>., agonistes, antagonistes et agonistes partiels) pour les récepteurs de dopamine (<i>e</i>.<i>g</i>., D¿1?, D¿2?, D¿3?, D¿4? et D¿5?) et notamment les récepteurs de dopamine D¿1?, D¿2? et D¿3?. La présente invention concerne aussi des procédés de conception rationnelle de ces composants et des procédés thérapeutiques de leur utilisation.
Ding Ke
Ji Min
Levant Beth
Varady Judith
Wang Shaomeng
Smart & Biggar
The Regents Of The University Of Michigan
LandOfFree
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