C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/32 (2006.01) A61K 31/395 (2006.01) C07D 207/08 (2006.01) C07D 401/04 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01)
Patent
CA 2146018
Fused tricyclic heteroaromatic compounds of formula (I) wherein one of X and Y represents nitrogen, and the other of X and Y represents oxygen, sulphur or N-R2; Q represent a substituted five- or six- membered monocyclic heteroaliphatic ring which contains one nitrogen atom as the sole heteroatom and is linked to the five-membered heteroatomic ring containing the moieties X and Y via a carbon atom as well as substitued 3,4-dihydro-1-hydroxy-2-oxomethyl-naphthalene precursors thereto, are ligands for dopamine receptor subtypes within the body and are therefore useful in the treatment of disorders of the dopamine system, in particular schizophrenia.
Leeson Paul David
Rowley Michael
Merck Sharp & Dohme Limited
Swabey Ogilvy Renault
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