Dopaminergic neuron proliferative progenitor cell marker msx1/2

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/09 (2006.01) C12N 5/0797 (2010.01) C12Q 1/04 (2006.01) C12Q 1/68 (2006.01) G01N 33/567 (2006.01) C07H 21/00 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2619736

Disclosed is a probe or primer for use in the detection of a growing progenitor cell of a dopamine-producing neuron. Also disclosed is an antibody. A polynucleotide probe or primer for use in the detection or screening of a growing progenitor cell of a dopamine-producing neuron, which can hybridize with the nucleotide sequence of Msx1 or Msx2 gene or a complementary sequence thereof; and an antibody directed against Msx1 or Msx2 protein for use in the detection or screening of a growing progenitor cell of a dopamine-producing neuron.

L'invention concerne une sonde ou une amorce employée dans la détection d'une cellule progénétrice de neurone à dopamine en pleine croissance. L'invention concerne également un anticorps. L'invention porte sur une sonde ou une amorce polynucléotidique employée dans la détection ou dans le criblage d'une cellule progénétrice de neurone à dopamine en pleine croissance, qui peut s'hybrider avec la séquence nucléotidique d'un gène Msx1 ou Msx2 ou avec une séquence complémentaire de ces derniers ; et sur un anticorps qui s'attaque à une protéine Msx1 ou Msx2 employée dans la détection ou dans le criblage d'une cellule progénétrice de neurone à dopamine en pleine croissance.

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