Dopaminergic neuron proliferative progenitor cell marker nato3

C - Chemistry – Metallurgy – 12 – Q

Patent

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Details

C12Q 1/68 (2006.01) C07H 21/00 (2006.01) C07K 16/18 (2006.01) C12N 15/12 (2006.01) C12Q 1/02 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2627593

Disclosed is a probe or primer for use in the detection of a growing progenitor cell of a dopamine-producing neuron. Also disclosed is an antibody. A polynucleotide probe or primer for use in the detection or screening of a growing progenitor cell of a dopamine-producing neuron, which can hybridize with the nucleotide sequence of Nato3 gene or a complementary sequence thereof; and an antibody directed against Nato3 protein for use in the detection or screening of a growing progenitor cell of a dopamine-producing neuron.

L~invention concerne une sonde ou un initiateur servant à la détection d~une cellule progénitrice de croissance de neurone producteur de dopamine. L~invention concerne également un anticorps. L~invention concerne en particulier une sonde ou un initiateur polynucléotide servant à la détection ou au criblage d~une cellule progénitrice de croissance de neurone producteur de dopamine, capable de s~hybrider avec la séquence nucléotidique du gène Nato3 ou une séquence complémentaire de celle-ci ; et un anticorps dirigé contre la protéine Nato3 servant à la détection ou au criblage d~une cellule progénitrice de croissance de neurone producteur de dopamine.

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