A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 31/167 (2006.01)
Patent
CA 2540045
The present invention is directed to a dosage form configured to provide the controlled release of an active agent formulation. A dosage form according to the present invention includes a reservoir containing an active agent formulation and an engine positioned at least partially within the reservoir. In order to reduce the possibility that the engine included in a dosage form of the present invention will separate from the reservoir either during or after fabrication of the dosage form of the present invention, the engine included in a dosage form according to the present invention is bonded to an inside surface of the reservoir. The present invention also includes methods for preparing a controlled release dosage form.
La présente invention concerne une forme posologique configurée pour assurer la libération contrôlée d'une formulation de principe actif. Une forme posologique de l'invention comprend un réservoir contenant une formulation de principe actif et un moteur placé au moins partiellement à l'intérieur du réservoir. Pour réduire la probabilité que le moteur inclus dans une forme posologique de l'invention se sépare du réservoir soit pendant soit après la fabrication de la forme posologique, le moteur est fixé à une surface intérieure du réservoir. L'invention concerne en outre des méthodes de préparation d'une forme posologique à libération contrôlée.
Capell Kimberly R.
Hatamkhany Zahedeh
Lam Andrew C.
Wiser Lauren M.
Yu Betty
Alza Corporation
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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