Dosage form having a saccharide matrix

Details Dosage form having a saccharide matrix Dosage form having a saccharide matrix

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 9/19 (2006.01) A61K 9/20 (2006.01) A61K 39/35 (2006.01) A61K 39/36 (2006.01) A61K 47/26 (2006.01) A61K 47/36 (2006.01) A61K 47/42 (2006.01)

Patent

CA 2516291

The present invention provides a non-compressed fast-dispersing solid dosage form suitable for oromucosal administration of a pharmaceutically active substance comprising (a) a first matrix forming agent in the form of maltodextrin having a dextrose equivalent (DE) of between 1 and 20,(b) a second matrix forming agent in the form of sorbitol, and (c) the active substance.

L'invention concerne une forme de dosage solide à dispersion rapide, non comprimée, appropriée à une administration oro-mucosale d'une substance pharmaceutiquement active comprenant : (a) un premier agent de formation de matrice se présentant sous la forme de maltodextrine présentant un équivalent de dextrose (DE) compris entre 1 et 20, (b) un second agent de formation de matrice se présentant sous la forme de sorbitol, et (c) la substance active.

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