A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/20 (2006.01) A61K 9/24 (2006.01) A61K 9/48 (2006.01) A61K 31/59 (2006.01) A61K 31/663 (2006.01) A61K 45/06 (2006.01)
Patent
CA 2454200
The present invention provides a gastric retention dosage form for immediate or uncontrolled release of a vitamin D derivative that stimulates calcium absorption from the intestine, like calcitriol, alphacalcidol and calcifediol, combined with delayed release of a bis-phosphonate calcium resorption inhibitor such as alendronic acid and its pharmaceutically acceptable salts and hydrates.
L'invention concerne une forme posologique à rétention gastrique destinée à libérer immédiatement et de manière non contrôlée un dérivé de vitamine D qui stimule l'absorption de calcium par l'intestin, notamment le calcitriol, l'alphacalcidol et le calcifediol, et à libérer de façon retardée un inhibiteur de la résorption du calcium à base de bis-phosphonate, notamment l'acide alendronique et ses sels et hydrates pharmaceutiquement acceptables.
Heenan Blaikie Llp
Teva Pharmaceutical Industries Ltd.
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