A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 9/20 (2006.01) A61K 31/35 (2006.01) A61K 31/4166 (2006.01) A61K 47/34 (2006.01) A61P 25/08 (2006.01)
Patent
CA 2489688
Dosage forms and devices for enhancing controlled delivery of pharmaceutical agents by use of a drug core composition containing a polymer carrier (e.g. polyethylene oxide) and a surfactant (e.g. polyoxyl stearate, poloxamer) that increases the solubility of the pharmaceutical agent are described. The present invention provides a means of delivering high doses of lowly soluble drug in oral drug delivery systems that are convenient to swallow, for once-a- day administration. Osmotic devices are described.
L'invention porte sur des formes posologiques et sur des dispositifs destinés à améliorer l'administration contrôlée d'agents pharmaceutiques au moyen d'une composition renfermant un médicament qui accroît la solubilité de l'agent pharmaceutique. La présente invention porte également sur un moyen d'administration de doses élevées d'un médicament faiblement soluble dans des systèmes d'administration par voie orale qui sont conçus pour être avalés, à raison d'une fois par jour.
Ayer Atul
Bhatti Gurdish
Edgren David
Jao Frank
Lam Andrew
Alza Corporation
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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