Dosage forms for weakly ionizable compounds

Details Dosage forms for weakly ionizable compounds Dosage forms for weakly ionizable compounds

A - Human Necessities

61

K

A61K 9/14 (2006.01)

Patent

CA 2735660

This disclosure relates to dosage forms (e.g., solid dosage forms) comprising a drug-containing emulsion, a drug-containing micro-emulsion, a self-emulsifying oil composition, or a self- microemulsifying oil composition, wherein each comprises a weakly ionizable drug and a pH modifier. Also provided are pharmaceutical dosage forms (e.g., solid dosage forms) and methods of preparing same.

La présente invention concerne des formes galéniques (par exemple, des formes galéniques solides) comprenant une émulsion contenant un médicament, une micro-émulsion contenant un médicament, une composition huileuse auto-émulsifiante ou une composition huileuse auto-microémulsifiante, chacune dentre elles comprenant un médicament faiblement ionisable et un modificateur de pH. Linvention concerne également des formes galéniques (par exemple, des formes galéniques solides) et leurs procédés de préparation.

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