Dosage forms that facilitate rapid activation of zymogen

Details Dosage forms that facilitate rapid activation of zymogen Dosage forms that facilitate rapid activation of zymogen

A - Human Necessities

61

K

A61K 47/06 (2006.01) A61K 38/48 (2006.01) A61P 17/00 (2006.01) C12N 9/00 (2006.01) C12N 9/50 (2006.01)

Patent

CA 2739403

The therapeutic efficacy of zymogen proteins for oral administration is improved by including in the formulation one or more excipients that optimize pH and other reaction conditions for rapid activation of the zymogen shortly after ingestion.

Selon l'invention, l'efficacité thérapeutique de protéines zymogènes pour une administration orale est améliorée en incluant dans la formulation un ou plusieurs excipients qui optimisent le pH et d'autres conditions de réaction pour une activation rapide du zymogène peu après l'ingestion.

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