A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/517 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2720987
In general, the invention relates to a pharmaceutical dose having (4-Methoxy-phenyl)-methyl-(2-methyl-quinazolin-4-yl)-amine hydrochloride as the active ingredient that upon administration to a subject provides a C max of about 1 ng/mL to about 250 ng/mL. The dose may be used in methods of treating cancer through the administration of (4-Methoxy-phenyl)-methyl-(2-methyl-quinazolin-4-yl)-amine hydrochloride. The composition of the invention is formulated with one or more pharmaceutically acceptable excipients, salts or carriers.
La présente invention concerne d'une manière générale une dose pharmaceutique contenant, comme ingrédient actif, du chlorhydrate de (4-Méthoxy-phényl)-méthyl-(2-méthyl-quinazolin-4-yl)-amine qui, lorsqu'il est administré à un sujet, permet d'obtenir une concentration Cmax comprise entre environ 1 ng/mL et environ 250 ng/mL. Cette dose peut être utilisée dans des méthodes de traitement du cancer comprenant l'administration de chlorhydrate de (4-Méthoxy-phényl)-méthyl-(2-méthyl-quinazolin-4-yl)-amine. La composition de cette invention est formulée avec un ou plusieurs excipients, sels ou vecteurs pharmaceutiquement acceptables.
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Myrexis Inc.
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