Dose response-based methods for identifying receptors having...

C - Chemistry – Metallurgy – 12 – Q

Patent

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C12Q 1/68 (2006.01) C12N 15/10 (2006.01) G01N 33/50 (2006.01) G01N 33/542 (2006.01) G01N 33/566 (2006.01)

Patent

CA 2452844

The invention provides methods of identifying receptors having altered signaling. In particular, the invention provides a sensitive dose response assay for the identification of receptors having alterations in ligand dependent or ligand independent signaling.

L'invention concerne des méthodes d'identification de récepteurs présentant une signalisation modifiée. Plus particulièrement, l'invention se rapporte à une analyse sensible fondée sur la relation dose-réponse et destinée à l'identification de récepteurs présentant des modifications de la signalisation dépendante ou indépendante d'un ligand.

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