Dosing regimes for lh or hcg and epo for treatment of...

A - Human Necessities – 61 – K

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A61K 38/24 (2006.01) A61K 38/18 (2006.01) A61P 25/28 (2006.01)

Patent

CA 2643502

Dosing regimes for neural stem cell proliferating agents in combination with neural stem cell differentiating agents, kits containing effective doses of neural stem cell proliferating agents and differentiating agents, and uses thereof in treating or ameliorating neurodegenerative diseases and conditions are disclosed. In particular, neural stem cell proliferating agent human chorionic gonadotropin (hCG) or luteinizing hormone (LH), administered in several doses, is used in combination with neural stem cell differentiating agent erythropoeitin (EPO). Other neural stem cell proliferating agents include prolactin.

L'invention concerne des régimes de dosage pour agents de prolifération de cellules souches nerveuses en combinaison avec des agents de différentiation des cellules souches, des trousses contenant des doses efficaces d'agents de prolifération de cellules souches nerveuses, et leur utilisation pour le traitement ou l'atténuation des maladies et manifestations neurodégénératives. En particulier, on administre systémiquement, à raison de plusieurs doses quotidiennes, de la gonadotropine chorionique humaine (hCG) ou une hormone lutéinisante (LH) comme agent de prolifération des cellules souches nerveuses en association avec de l'érythropoïétine (EPO), agent de différentiation des cellules souches nerveuses.

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