Dot matrix membrane cell expansion and maintenance vessel

Details Dot matrix membrane cell expansion and maintenance vessel Dot matrix membrane cell expansion and maintenance vessel

C - Chemistry, Metallurgy

12

N

195/145, 195/46

C12N 5/00 (2006.01) C12M 1/00 (2006.01) C12M 3/00 (2006.01) C12M 3/06 (2006.01)

Patent

CA 2002020

-1- TITLE DOT MATRIX MEMBRANE CELL EXPANSION AND MAINTENANCE ABSTRACT OF THE DISCLOSURE There is disclosed a perfusable cell culture device capable of expansion and maintenance of biological cells, including mammalian, micorbial, plant and insect cells in culture. The device comprises an upper and lower polymeric film layer and a gas and liquid permeable flow divider membrane. The flow divider memberane is affixed between the upper and lower polymeric layers and to the lower polymeric layer in a manner providing channels for fluid distribution of culturer medium which is perfused at a controlled rate, unformly across the flow divider membrane and to a bed of cells dispersed on the flow divider membrane.

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