C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
167/202, 260/228
C07H 5/04 (2006.01) A61K 31/70 (2006.01) C07D 233/88 (2006.01) C07H 15/26 (2006.01)
Patent
CA 1238318
ABSTRACT Double salt, process for its preparation and pharmaceutical composition containing it. The double sulfate of 1-desoxy-(5-hydroxytryptamino)- D-fructose (DFS) and 1-methylhydantoin-2-imide (creatinine) represents a new solid crystalline phase of unit composition, pharmaceutical quality and remarkable stability. It is prepared by glycosylation of serotonin with D- glucose, formation of the double salt by addition of sulfuric acid and creatinine and crystallization of the double salt in the presence of ethanol. The DFS is preferably isolated from the reaction medium by way of the addition complex DFS.Ca(OH)2 which is precipitated by the addition of calcium hydroxide. The calcium hydroxide is then eliminated by addition of sulfuric acid and the double salt crystallized as described above. The DFS is the active principle of a medicament effective in particular in the treatment of leprosy.
487348
Bertholet Raymond
Hirsbrunner Pierre
Borden Ladner Gervais Llp
Societe Des Produits Nestle S.a.
LandOfFree
Double salt, process for its preparation and pharmaceutical... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Double salt, process for its preparation and pharmaceutical..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Double salt, process for its preparation and pharmaceutical... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1214542