Double stranded rna as an adjuvant in vaccine compositions

Details Double stranded rna as an adjuvant in vaccine compositions Double stranded rna as an adjuvant in vaccine compositions

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 9/14 (2006.01) A61K 39/39 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2462602

Adjuvant compositions comprising type 1 interferon inducers, such as double- stranded RNA, in combination with antigen delivery systems and/or immunostimulatory molecules, such as immunostimulatory nucleic acid sequences, for enhancing the immune response of a coadministered antigen, are described.

L'invention concerne des compositions d'adjuvants comprenant des inducteurs d'interféron de type 1, tels que l'ARN bicaténaire, associées à des systèmes d'administration d'antigènes et/ou à des molécules immunostimulantes, notamment des séquences d'acide nucléique immunostimulantes, permettant de favoriser la réponse immunitaire d'un antigène coadministré.

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