Down-regulation of target-gene with pei/single-stranded...

Details Down-regulation of target-gene with pei/single-stranded... Down-regulation of target-gene with pei/single-stranded...

A - Human Necessities

61

K

A61K 48/00 (2006.01) A61K 31/105 (2006.01) A61K 31/7105 (2006.01) A61K 31/7115 (2006.01) A61K 47/48 (2006.01) C12N 15/11 (2006.01) C12N 15/85 (2006.01) C12Q 1/68 (2006.01) A61K 38/00 (2006.01) C12N 15/87 (2006.01)

Patent

CA 2514536

The present invention provides methods for the downregulation of target genes by an RNA interference mechanism using short single stranded RNA and a cationic polymer, such as linear PEI.

La présente invention porte sur des procédés de régulation négative de gènes cibles faisant appel à un mécanisme d'interférence de l'ARN utilisant un ARN simple brin court et un polymère cationique, tel qu'un PEI linéaire.

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