Down syndrome screening method utilizing dried blood samples

Details Down syndrome screening method utilizing dried blood samples Down syndrome screening method utilizing dried blood samples

G - Physics

01

N

G01N 33/76 (2006.01) G01N 33/543 (2006.01)

Patent

CA 2141870

The present invention relates to a method for detecting fetal Down syndrome (Trisomy 21), trisomy 13, trisomy 18 and other chromosomal anomalies during prenatal screening by analyzing a dried blood sample from a pregnant woman. More particularly the present invention relates to a method for improving detection efficiency in screening for the anomalies by measuring the amount of the free beta human chorionic gonadotropin (HCG) and nicked or fragmented or aberrant forms of free beta (HCG), all of which are referenced throughout this application as free beta (HCG) in dried blood samples from pregnant women.

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