C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 31/00 (2006.01) A61K 38/00 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01) C07K 16/30 (2006.01) C07K 16/46 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2518695
The present invention is directed to negative modulators of CA 125 tumor antigen, a recombinant nucleic acids, vectors, host cells, pharmaceutical compositions, uses of the foregeoing for negatively modulating CA 125 tumor antigen in mammalian cell, preventing and treating a CA 125 tumor antigen associated disease in a mammal, as well as methods of prevention and treatment of such diseases and methods of negatively regulating CA 125 tumor antigen in a mammalian cell.
L'invention concerne des modulateurs de l'antigène tumoral CA 125, des acides nucléiques recombinés, des vecteurs, des cellules hôtes, des compositions pharmaceutiques, l'utilisation de ces modulateurs dans la modulation négative de l'antigène tumoral CA 125 dans une cellule mammifère, la prévention et le traitement d'une maladie associée à l'antigène tumoral CA 125 chez un mammifère, des méthodes de prévention et de traitement de telles maladies ainsi que des méthodes de régulation négative de l'antigène tumoral CA 125 dans une cellule mammifère.
Beaudin Julie
Piche Alain
Rancourt Claudine
Robic
Universite de Sherbrooke
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