Dpp iv inhibitor for use in the treatment of autoimmune...

A - Human Necessities – 61 – K

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A61K 31/40 (2006.01) A61P 3/10 (2006.01) A61P 17/06 (2006.01) A61P 37/06 (2006.01)

Patent

CA 2623826

The present invention relates to a combination, such as a combined preparation or pharmaceutical composition, respectively, comprising of a DPP IV inhibitor or a pharmaceutically acceptable salt thereof and comprising at least one immunosuppressive or immunomodulator agent, or a pharmaceutically acceptable salt thereof. The present invention furthermore relates to the use of such a combination for the prevention, delay of progression or treatment of diseases and disorders that may be inhibited by DPP IV inhibition, for the prevention, delay of progression or treatment of autoimmune diseases, and the disorders associated therewith, or for the prevention, delay of progression or treatment of graft rejection.

La présente invention concerne une combinaison, telle qu'une préparation ou une composition pharmaceutique combinée, respectivement, constituée d'un inhibiteur de la DPP IV ou d'un sel acceptable du point de vue pharmaceutique de celui-ci et comprenant au moins un agent immunodépresseur ou immunomodulateur, ou un sel acceptable du point de vue pharmaceutique de celui-ci. La présente invention concerne en outre l'utilisation d'une telle combinaison pour la prévention, le retardement de la progression ou le traitement de maladies et troubles qui peuvent être inhibés par l'inhibition de la DPP IV, pour la prévention, le retardement de la progression ou le traitement de maladies autoimmunes et des troubles associés à celles-ci ou pour la prévention, le retardement de la progression ou le traitement du rejet de greffe.

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