C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/77 (2006.01) A61K 31/34 (2006.01) A61P 25/00 (2006.01) C12N 1/14 (2006.01) C12P 17/04 (2006.01)
Patent
CA 2473988
The invention relates to novel, Drechslera anoles of known compounds of formula (I), which are formed during fermentation of the microorganisms Drechslera australiensis, ST 003360, DSM 14093, or ST 004112, DSM 14524. The invention also relates to a method for the production thereof, the use of said Drechslera anoles as medicaments, especially in the treatment and/or prophylaxis of degenerative neuropathies, for example, Alzheimer's disease or mental illnesses, such as depression, sleep disorders or seasonally related disorders, and the use of Drechslera anoles as chelating agents or antioxidants.
La présente invention concerne de nouveaux composés de formule (I) appelés anoles de Drechslera, formés pendant la fermentation par les micro-organismes Drechslera australiensis, ST 003360, DSM 14093 ou ST 004112, DSM 14524. Cette invention concerne également un procédé de production desdits composés, l'utilisation d'anoles de Drechslera comme médicaments, en particulier dans le traitement et/ou la prophylaxie de neuropathies dégénératives, par exemple la maladie d'Alzheimer, ou des troubles psychiques, tels que la dépression, des troubles du sommeil ou des troubles affectifs saisonniers, et l'utilisation d'anoles de Drechslera comme chélateurs ou antioxydants.
Eder Claudia
Kurz Michael
Toti Luigi
Aventis Pharma Deutschland Gmbh
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Sanofi-Aventis Deutschland Gmbh
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