A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/00 (2006.01) A61K 31/695 (2006.01) A61K 47/10 (2006.01) A61K 47/14 (2006.01) A61K 47/24 (2006.01)
Patent
CA 2499900
There are provided safe, tasteless, odorless, non-aqueous liquid spray compositions formulated for administration to the nasal cavity consisting essentially of pharmacologically acceptable non aqueous liquid carrier in which said bioactive material is directly insoluble, a pharmacologically acceptable water insoluble ester of a water soluble acid soluble in said carrier, a pharmacologically acceptable water soluble glycol soluble in said ester and a pharmacologically acceptable water soluble bio-active material soluble in said glycol but not directly soluble in the carrier. There are also provided methods of producing and administering such compositions.
L'invention concerne des compositions de vaporisation liquides non aqueuses sans odeur sans goût et non nocives à la santé, formulées pour une administration dans la cavité nasale. Ces compositions comportent essentiellement un excipient liquide non aqueux pharmacologiquement acceptable, dans lequel la matière bioactive est directement insoluble, un ester insoluble dans l'eau pharmacologiquement acceptable d'un acide soluble dans l'eau, soluble dans ledit excipient, un glycol soluble dans l'eau pharmacologiquement acceptable, soluble dans ledit ester, et une matière bioactive soluble dans l'eau pharmacologiquement acceptable, soluble dans ledit glycol, mais non directement soluble dans l'excipient. L'invention concerne des méthodes de production et d'administration de telles compositions.
Mackles Leonard
Goudreau Gage Dubuc
Mackles Leonard
LandOfFree
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