A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 9/127 (2006.01) A61K 38/18 (2006.01) A61K 47/18 (2006.01) C07K 14/51 (2006.01)
Patent
CA 2664637
The present invention relates to dried reconstituted vesicle (DRV) compositions and water based formulations thereof, which contain one or more therapeutic agents (e.g. hydrophilic protein). More particularly, it relates to DRVs comprising at least one lipid and a fusion promoting agent which after reconstitution form large multilamellar liposomes encapsulating an active agent in an aqueous phase.
La présente invention concerne des compositions de vésicules reconstituées séchées (Dried Reconstituted Vesicle : DRV) et des formulations à base d'eau de celles-ci, qui contiennent un ou plusieurs agents thérapeutiques (par exemple une protéine hydrophile). L'invention concerne plus particulièrement des DRV qui comprennent au moins un lipide et un agent favorisant la fusion qui, après reconstitution, forment de grands liposomes plurilamellaires qui encapsulent un agent actif dans une phase aqueuse.
Hellerbrand Klaus
Schuetz Andreas
Sigl Rainer
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
Scil Technology Gmbh
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