Drug coating providing high drug loading and methods for...

A - Human Necessities – 61 – K

Patent

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A61K 9/24 (2006.01)

Patent

CA 2540308

The present invention is directed to aqueous drug coatings that include at least one insoluble drug, wherein the drug accounts for about 85 wt% to about 97 wt% of the drug coatings. A drug coating according to the present invention may include only one insoluble drug, two or more insoluble drugs, or one or more insoluble drugs in combination with one or more soluble drugs. The present invention also includes drug coating formulations suitable for providing drug coatings according to the present invention and dosage forms that include a drug coating according to the present invention.

L'invention concerne des enrobages de médicaments aqueux qui contiennent au moins un médicament insoluble, le médicament contenant entre environ 85 et environ 97 % en poids de ces enrobages de médicaments. Selon l'invention, l'enrobage peut ne contenir qu'un seul médicament insoluble, au moins deux médicaments insolubles, ou au moins un médicament insoluble en combinaison avec au moins un médicament soluble. Par ailleurs, l'invention concerne des formulations d'enrobage de médicaments qui permettent d'obtenir les enrobages de médicaments décrits ainsi que des formes dosifiées qui contiennent un enrobage de médicament de l'invention.

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