A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4965 (2006.01) A61K 31/496 (2006.01) A61K 45/06 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 17/06 (2006.01) A61P 17/10 (2006.01) A61P 25/28 (2006.01) A61P 35/00 (2006.01) C07D 295/20 (2006.01)
Patent
CA 2725933
The present invention relates to combinations of a DGAT inhibitor and a peroxisome proliferator-activator receptor (PPAR) agonist or a prodrug thereof. The invention further relates to methods for preparing such combinations, pharmaceutical compositions comprising said combinations as well as the use as a medicament of said combinations. The present invention also relates to novel DGAT inhibitors. The invention further relates to methods for preparing such compounds, pharmaceutical compositions comprising said compounds as well as the use as a medicament of said compounds.
La présente invention porte sur des combinaisons d'un inhibiteur de DGAT et d'un agoniste du récepteur proliférateur-activateur du peroxisome (PPAR) ou un promédicament de celui-ci. L'invention porte en outre sur des procédés pour préparer de telles combinaisons, sur des compositions pharmaceutiques comprenant lesdites combinaisons ainsi que sur l'utilisation en tant que médicament desdites combinaisons. La présente invention porte également sur de nouveaux inhibiteurs de DGAT. L'invention porte en outre sur des procédés de préparation de tels composés, sur des compositions pharmaceutiques comprenant lesdits composés, ainsi que sur l'utilisation en tant que médicament desdits composés.
Hrupka Brian Joel
Linders Joannes Theodorus Maria
Roevens Peter Walter Maria
Gowling Lafleur Henderson Llp
Janssen Pharmaceutica N.v.
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