Drug composition containing nf-.kappa.b inhibitor

A - Human Necessities – 61 – K

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A61K 31/167 (2006.01) A61K 31/336 (2006.01) A61K 45/00 (2006.01) A61P 9/10 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2500165

A drug composition for ameliorating the symptoms attributed to tumor cells, comprising a compound represented by the general formula (1) or a pharmaceutically acceptable salt thereof as an active ingredient. General formula: (1) wherein R1 represents hydrogen or a C2-4 alkanoyl group; and R2 represents a group of any of the following formulae: (A) - (G) in which R3 represents a C1-4 alkyl group.

Cette composition médicinale, destinée à atténuer les symptômes occasionnés par des cellules tumorales, renferme un composé, correspondant à la formule générale (I), ou un sel de celui-ci, acceptable du point de vue pharmaceutique, comme ingrédient actif. Dans cette formule, R?1¿ représente un hydrogène ou un groupe alcanoyle ayant de 2 à 4 atomes de carbone et R?2¿ représente un groupe correspondant aux formules suivantes (A - G), formules dans lesquelles R?3¿ représente un groupe alkyle ayant de 1 à 4 atomes de carbone.

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