A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/4035 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 13/12 (2006.01) A61P 27/02 (2006.01) A61P 43/00 (2006.01)
Patent
CA 2489660
A drug composition capable of attaining a good state of blood sugar control so as to enable correcting postprandial high blood sugar levels or high blood sugar levels at early fasting time. In particular, a drug composition for prevention or inhibition of advance of diabetic complications to be taken before meals, comprising 5 to 45 mg, in terms of one-time dose, of mitiglinide or its pharmacologically acceptable salt or a hydrate thereof (e.g., mitiglinide calcium salt hydrate). The drug composition is highly useful for the prevention or inhibition of advance of, for example, diabetic microangio complications and arteriosclerosis because the ratio of occurrence of side effects, such as low blood sugar level symptom and gastrointestinal tract disorder, is low.
La présente invention concerne une composition médicamenteuse permettant de parvenir à une bonne régulation de la glycémie dans le but de corriger des taux élevés de glycémie postprandiale ou des taux élevés de glycémie à jeun. En particulier, l'invention concerne une composition médicamenteuse pour la prévention ou l'inhibition de la progression des complications diabétiques, qui doit être prise avant les repas à raison d'une dose unique de 5 à 45 mg de mitiglinide ou d'un de ses sels ou hydrates pharmaceutiquement acceptables (par exemple un hydrate de calcium de mitiglinide). Cette composition médicamenteuse est extrêmement utile pour la prévention ou l'inhibition de la progression des complications diabétiques et de l'artériosclérose du fait du faible taux de survenue des effets secondaires, du type symptôme d'hypoglycémie et trouble du tractus gastro-intestinal.
Kiyono Yuji
Mikoshiba Imao
Suzuki Hisao
Kirby Eades Gale Baker
Kissei Pharmaceutical Co. Ltd.
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