Drug composition having active ingredient adhered at high...

A - Human Necessities – 61 – K

Patent

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A61K 9/16 (2006.01) A61K 9/22 (2006.01) A61K 9/32 (2006.01) A61K 9/52 (2006.01) A61K 31/4439 (2006.01) A61P 1/04 (2006.01) A61P 43/00 (2006.01)

Patent

CA 2518780

Granule, fine particle or tablet of excellent leaching property, comprising a drug active ingredient in high content realized by forming a layer containing drug active ingredient on core particles through a combination of a method of dispersing and adhering an active ingredient while spraying or adding a binder with a method of spraying or adding a solution or suspension wherein an active ingredient and a binder are contained so as to effect adhesion. Further, there are provided a drug composition containing such a granule, fine particle or tablet and a process for producing the same.

L'invention concerne un granule, une fine particule ou un comprimé présentant une excellente propriété de lessivage, comprenant un principe actif médicamenteux en une teneur élevée réalisé par formation d'une couche contenant un principe actif médicamenteux sur des particules de noyau par une combinaison d'un procédé de dispersion et d'adhésion d'un principe actif tout en pulvérisant ou en ajoutant un liant, selon un procédé de pulvérisation ou d'ajout d'une solution ou d'une suspension dans lequel un principe actif et un liant sont contenus de manière à effectuer l'adhésion. De plus, l'invention concerne une composition de médicament contenant ce granule, cette fine particule ou ce comprimé et un procédé pour leur production.

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