Drug containing (2r)-2-propyloctanoic acid as the active...

Details Drug containing (2r)-2-propyloctanoic acid as the active... Drug containing (2r)-2-propyloctanoic acid as the active...

A - Human Necessities

61

K

A61K 31/20 (2006.01) A61K 9/06 (2006.01) A61K 9/08 (2006.01) A61K 9/10 (2006.01) A61K 47/02 (2006.01) A61P 25/00 (2006.01) A61P 25/28 (2006.01) C07C 51/41 (2006.01) C07C 53/128 (2006.01)

Patent

CA 2540670

A drug containing from about one to five equivalents of a basic metal ion supplied from a metal salt of a weak acid or a metal hydroxide per equivalent of (2R)-2-propyloctaonic acid or its salt, which is useful in treating neurodegenerative diseases, optionally together with other additives. The above-described rug is a high-concentration drug which has a pH value suitable for intravenous administration, is highly tolerant to pH changes and remains transparent after diluted to prepare an infusion, thereby enabling the preparation of an injection and so on with the use of an arbitrary solvent and/or a diluting fluid.

L'invention concerne un médicament contenant entre environ un et cinq équivalents d'un ion métallique de base acheminé depuis un sel métallique d'un acide faible ou d'un hydroxyde métallique par équivalent d'acide (2R)-2-propyloctanoïque ou ses sels que l'on utilise dans le traitement des maladies neurodégénératives, éventuellement accompagné d'autres additifs. Le médicament de cette invention est un médicament à forte concentration présentant une valeur pH apte à une administration intraveineuse, il est très tolérant aux variations de pH et reste transparent après avoir été dilué dans le but de préparer une infusion, ce qui permet de préparer une injection, etc. à l'aide d'un solvant arbitraire et/ou d'un fluide de dilution.

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