Drug containing chymase inhibitor as the active ingredient

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/506 (2006.01) A61K 31/397 (2006.01) A61K 31/4184 (2006.01) A61K 31/422 (2006.01) A61K 45/00 (2006.01) A61P 3/00 (2006.01) A61P 3/04 (2006.01) A61P 3/10 (2006.01) A61P 9/00 (2006.01) A61P 9/10 (2006.01) A61P 9/12 (2006.01) A61P 13/12 (2006.01) A61P 25/02 (2006.01) A61P 25/28 (2006.01) A61P 27/02 (2006.01)

Patent

CA 2536435

An agent for improving abnormal glucose tolerance or a preventive and/or a remedy for diseases caused by abnormal glucose tolerance containing a chymase inhibitor as the active ingredient. Examples of the diseases caused by abnormal glucose tolerance include diabetes and/or complications of diabetes. Examples of the complications of diabetes include diabetic nephropathy, diabetic retinopathy, diabetic peripheral neuropathy, hyperinsulinemia, insulin resistance syndrome, arteriosclerosis, acute coronary syndrome, arteriosclerosis obliterans, vasculitis, brain infarction, hypertension, renal insufficiency, neuropathy, nephritis, renal aneurysm, renal infarction, obesity and so on.

L'invention concerne un agent de traitement d'une tolérance au glucose anormale, ou un agent préventif et/ou un remède destinés à des maladies causées par une tolérance au glucose anormale, contenant un inhibiteur de chymase en tant qu'agent actif. Des maladies causées par une tolérance au glucose anormale peuvent être le diabète ou des complications diabétiques. Les complications diabétiques peuvent être du type néphropathie diabétique, rétinopathie diabétique, neuropathie périphérique diabétique, hyperinsulinémie, syndrome de résistance à l'insuline, artériosclérose, syndrome coronaire grave, occlusion artériosclérotique, vasculite, attaque cérébrale, hypertension, insuffisance rénale, neuropathie, néphrite, anévrisme rénal, infarctus rénal, obésité etc.

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