Drug-containing solid dispersion having improved solubility

Details Drug-containing solid dispersion having improved solubility Drug-containing solid dispersion having improved solubility

A - Human Necessities

61

K

A61K 9/14 (2006.01) A61K 9/16 (2006.01) A61K 9/20 (2006.01) A61K 45/00 (2006.01) A61K 47/04 (2006.01) A61K 47/30 (2006.01) A61K 47/32 (2006.01) A61K 47/34 (2006.01) A61K 47/36 (2006.01) A61K 47/38 (2006.01)

Patent

CA 2418490

A solid dispersion composition which is prepared by radiating a composition comprising a sparingly soluble drug and a water-soluble polymeric material with a microwave; and a method for preparing the solid dispersion composition. The solid dispersion composition exhibits improved solubility and also can be prepared by a simple process at a low cost, and further is excellent in safety.

La présente invention concerne une composition de dispersion solide qui s'obtient en exposant à un rayonnement hyperfréquences une composition comprenant un médicament à peine soluble et un matériau polymère hydrosoluble. L'invention concerne également un procédé permettant l'élaboration de cette composition pour dispersion solide. En l'occurrence, cette composition pour dispersion solide, qui fait preuve d'une meilleure solubilité, s'obtient selon un procédé simple bon marché, tout en présentant une très bonne sécurité.

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