Drug delivery collagen synthetic vascular graft

Details Drug delivery collagen synthetic vascular graft Drug delivery collagen synthetic vascular graft

A - Human Necessities

61

F

128/104, 3/122,

A61F 2/06 (2006.01) A61K 47/00 (2006.01) A61L 27/00 (2006.01) A61L 27/34 (2006.01) A61L 27/50 (2006.01) A61L 27/54 (2006.01)

Patent

CA 1250235

-14- ABSTRACT OF THE DISCLOSURE A collagen-impregnated vascular graft including drug materials complexed with the collagen to be released slowly from the graft following implant. The graft is a porous synthetic vascular graft substrate having collagen fixed to the graft substrate and cross-linked in situ to render the porous substrate blood-tight. The drug materials complexed with the collagen fibrils may include antithrombic agents, antibacterial, antimicrobial agents, anti- fungal agents and the like.

473090

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