A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/155 (2006.01) A61K 6/00 (2006.01) A61K 9/00 (2006.01) A61K 45/06 (2006.01) A61K 9/20 (2006.01)
Patent
CA 2275049
A drug delivery composition is disclosed that can achieve the sustained release of biologically active agents. Preferred is a composition having a dental application in the root canals and pulp chambers of teeth. A particularly preferred composition is a non-biodegradable device capable of achieving the sustained release of antimicrobial agents. The composition can be formed into insert devices, that can be used to treat and prevent endodontic diseases and conditions. The insert devices are especially useful in treating and preventing diseases such as periradicular periodontitis, apical abscess and external inflammatory root resorption, all of which require drug delivery to the root canals and pulp chambers of the affected teeth. Preferably, the composition contains chlorhexidine and its salts , that can be released to sustain high concentrations in root canals of teeth over a period of up to three months.
Friedman Shimon
Grad Helen
Huang Junfu
Wu Xiao Yu
Friedman Shimon
Grad Helen
Huang Junfu
Riches Mckenzie & Herbert Llp
Wu Xiao Yu
LandOfFree
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