Drug delivery device comprising an active compound and...

Details Drug delivery device comprising an active compound and... Drug delivery device comprising an active compound and...

C - Chemistry, Metallurgy

08

J

C08J 3/28 (2006.01) A61K 9/00 (2006.01) A61K 47/30 (2006.01) B06B 3/00 (2006.01) B29C 71/04 (2006.01)

Patent

CA 2530003

The present invention relates to a drug delivery device for implantation in a mammalian body comprising a solid polymeric material having a barrier effect against diffusion of an active compound and having a glass transition temperature within the range of about 0~ to about 90~ C and an active compound, wherein the characteristics of diffusion or transport of the active compound can be modified in a reversible manner by supplying energy from an energy source. The present invention also relates to a method for releasing an active compound from a drug delivery device.

L'invention concerne un dispositif d'administration de médicaments à implanter dans le corps d'un mammifère et comprenant un matériau polymère solide ayant un effet de barrière contre la diffusion d'un composé actif et possédant une température de transition vitreuse comprise dans la gamme allant d'environ 0· à environ 90· C et un composé actif, les caractéristiques de diffusion ou de transport du composé actif pouvant être modifiées d'une manière réversible au moyen d'une alimentation d'énergie à partir d'une source d'énergie. L'invention concerne également un procédé permettant de libérer un composé actif d'un dispositif d'administration de médicaments.

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