Drug delivery device, especially for the delivery of androgens

Details Drug delivery device, especially for the delivery of androgens Drug delivery device, especially for the delivery of androgens

A - Human Necessities

61

K

A61K 9/00 (2006.01) A61K 38/22 (2006.01)

Patent

CA 2351064

The invention relates to a delivery device for the controlled release of a therapeutically active agent, especially an androgen, over a prolonged period of time, said device comprising a core comprising said therapeutically active agent, and a membrane encasing said core wherein said membrane is made of an elastomer. According to the invention, the elastomer is a siloxane-based elastomer comprising 3,3,3-trifluoropropyl groups attached to the Si-atoms of the siloxane units.

L'invention concerne un dispositif d'administration permettant la libération contrôlée d'un agent thérapeutiquement actif, en particulier un androgène, pendant une durée prolongée. Ledit dispositif comprend un noyau renfermant ledit agent thérapeutiquement actif, et une membrane enveloppant ledit noyau. Ladite membrane est faite d'un élastomère. L'élastomère est à base de siloxane comprenant des groupes 3,3,3-trifluoropropyle fixés aux atomes de Si des unités de siloxane.

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