Drug delivery device, its preparation and use

Details Drug delivery device, its preparation and use Drug delivery device, its preparation and use

A - Human Necessities

61

K

128/104

A61K 9/70 (2006.01)

Patent

CA 1272922

A B S T R A C T Drug Delivery Device, Its Preparation and Use A device suitable for the topical administration of a pharmacologically active agent to an animal is described. The device comprises an active agent impermeable barrier layer, a reservoir containing the active agent which is in contact with the inner surface of the barrier layer and a removable protector layer in contact with the other surface of the reservoir. The reservoir comprises a fibrous mat into which the pharmacologically active agent is incorporated either by dissolving in the polymer forming the mat or by impregnation of a preformed mat. Alternative forms of the reservoir comprise a fibre mat coated on a skin contacting surface with a pressure sensitive adhesive and a fibre mat contained within a gel matrix. The device may be used to deliver nitroglycerin, oxybutynin or phenazocine transdermally.

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